Endocrine Abstracts

In the adrenal incidentaloma (AI) it is fundamental to determine functionality and benignity. The aim of this study was to evaluated the clinical, radiological and hormonal evolution of AI and compare the frequency of autonomous cortisol secretion (ACS) between American and European Guidelines.Methods: Retrospective evaluation of patients with AI referred to our service in the last 5 years.Results: 140 patients were included, 50.9%...

Background: Retroperitoneal Schwannomas are rare and generally benign tumors originating from the neural sheath. In particular, juxta-adrenal schwannomas may be misdiagnosed as adrenal tumors due to their location and radiological characteristics.Case Presentation: A 40-year-old female patient referred to our outpatient clinic owing to a left suprarenal mass of 35 mm incidentally discovered in an enhanced CT. She was asymptomatic and the clinical examina...

Introduction: The Carney-Stratakis syndrome (CSS) is an inherited condition caused by germline mutations in succinate dehydrogenase (SDH) subunits B, C or D that predispose to gastric stromal tumors (GIST) and multicentric paragangliomas (PGL). SDH acts as a tumor suppressor gene, and enzyme activity reduction is known to be oncogenic. Since 2002 there has been some scarce reports. We present a new case of CSS associated with a germline unknown significance mutation in exon 4 ...